Currently, every technology in the field of genetics is being linked to CRISPR so as to remake the world. CRISPR is currently turning out to be one of the most commonly used genome-editing tools so as to help the practitioners and researchers help eradicate the most dangerous diseases in humanity using its property of editing. The use of the current technology helps slice and stitch the DNA strands but the presence of various DNA-breaking enzymes may hinder the entire process. The precise technique called base editing is being practiced so as to carry out the process error-free. The new base editor technique is being tested by scientists from across the world which are raising a lot of questions owing to the mess caused in specific genomes.
The idea of rushing the use of base editor in the humans is quite concerning after the CRISPR baby controversy and also the 20-fold increase in the mutations in comparison to the normal cell-division process. The developers of the base editor Harvard and the Broad Institute researchers are clueless about the future clinical impacts. The CRISPR technique helps to reduce the mutation levels but there are some variations also that follow in the genetic level which is something hard to accept by the scientific society. The use of algorithm and error-detection technologies can help keep an eye on the CRISPR techniques editing in order to help maintain precision. The National Institutes of Health will be granted $190 million so as to help develop a safer and standard therapeutic genome-editing tool.
The error rate that can be considered acceptable is something the researchers are currently working on but to date, there is no hard and fast rule for the error numbers. The futuristic CRISPR-based medicines and technologies can help eliminate some of the dreadful diseases. Recently, CRISPR Therapeutics had carried out its first test of treating beta-thalassemia patients with the technology so as to understand its effect on the genetic diseases. The CRISPR-based medicines still have time to go mainstream due to the various unknown factors standing in its way.